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Elafin Antibody

CAT: 0800-RQ4509Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4509Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Elafin, also known as peptidase inhibitor 3 or skin-derived antileukoprotease (SKALP), is a protein that in humans is encoded by the PI3 gene. This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. And this gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Capture ELISA: 1-5 µg/mL (human recombinant protein)
UniProt
P19957
Host
Mouse
Reactivity
Human
Immunogen
Human Elafin/Skalp recombinant protein (amino acids A61-Q117) was used as the immunogen for the Elafin antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
C7
Applications
IHC-P, ELISA
Purity
Protein G affinity
Format
Purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Elafin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Elafin antibody is available for research use only.
Storage Conditions
After reconstitution, the Elafin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Elafin antibody should be determined by the researcher.
Location
Secreted
Image Legend
IHC testing of FFPE human tonsil tissue with Elafin antibody at 2ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.

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