Elastin Antibody

• Description:

  Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.

• Specifications:

  IHC (FFPE) : 0.25-0.5 µg/mL

• Host:

  Mouse

• Reactivity:

  Human, Bovine

• Immunogen:

  Bovine alpha-elastin was used as the immunogen for this Elastin antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  BA-4

• Applications:

  IHC-P

• Purity:

  Ascites

• Format:

  Ascites

• Buffer:

  0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS

• Reconstitution:

  After reconstitution, the Elastin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This Elastin antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the Elastin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS

• Applications Notes:

  The stated application concentrations are suggested starting amounts. Titration of the Elastin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4