Elastin Antibody

CAT: 0800-V3832-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0800-V3832-20UGSize:20 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
CAS Number
9007-83-4
Specifications
ELISA (order BSA/sodium azide-free format for coating), Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P15502
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full length human protein was used as the immunogen for the Elastin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ELN/1981
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Elastin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Elastin antibody is available for research use only.
Storage Conditions
Store the Elastin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Titering of the Elastin antibody may be required for optimal performance.
Location
Secreted
Image Legend
IHC testing of FFPE human small intestine with Elastin antibody (clone ELN/1981) . Required HIER: boiling tissue sections in 10mM citrate buffer, pH 6, for 10-20 min and allow to cool prior to staining.
Product Datasheet
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