Products for Research Use Only
RegisterLogin

SCNN1A Antibody

CAT: 0800-RQ4301Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ4301Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The SCNN1A gene encodes the alpha subunit of the epithelial sodium channel (ENaC), a constitutively active channel that allows the flow of sodium ions from the lumen into epithelial cells across the apical cell membrane. The ENaC channel, which is regulated by the renin-angiotensin-aldosterone system, has a central role in the regulation of extracellular fluid volume and blood pressure. The other subunits are encoded by the beta (SCNN1B), gamma (SCNN1G), and delta (SCNN1D) genes. This SCNN1A gene is mapped to 12p13.31. Mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL
UniProt
P37088
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids QEWVFQMLSRQNNYTVNNKRNGVAKVNIFFKELNYK were used as the immunogen for the SCNN1A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the SCNN1A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SCNN1A antibody is available for research use only.
Storage Conditions
After reconstitution, the SCNN1A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SCNN1A antibody should be determined by the researcher.
Location
Cell membrane
Image Legend
Immunofluorescent staining of FFPE human A431 cells with SCNN1A antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

Related Products

CatalogName
RQ6208SCN2A Antibody
RQ6514SCN1B Antibody
RQ6209Scn2a Antibody
F54191-0.2MLSCN1A Antibody / Nav1.1 (Center Region)
F54191-0.05MLSCN1A Antibody / Nav1.1 (Center Region)
R32077SCN1A Antibody / Nav1.1 (C-Terminal Region)
FY12120SCNM1 Antibody / Sodium channel modifier 1
F55119-0.4MLSCN1B Antibody / Sodium channel subunit beta-1
F55119-0.08MLSCN1B Antibody / Sodium channel subunit beta-1
RQ4624NONO Antibody / p54nrb Antibody

Alternative Products

CatalogName
DF9199-01SCNN1A Antibody

Popular Products