Scn2a Antibody

CAT: 0800-RQ6209Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ6209Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nav-alpha 1.2, also known as the sodium channel, voltage-gated, type II, alpha subunit is a protein that in humans is encoded by the SCN2A gene. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. Allelic variants of this gene are associated with seizure disorders and autism spectrum disorder. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL
UniProt
B1AWN6
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Amino acids RTMNMFNWDEYIEDKSH from the mouse protein were used as the immunogen for the Scn2a antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.0125% sodium azide
Reconstitution
After reconstitution, the Scn2a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Scn2a antibody is available for research use only.
Storage Conditions
After reconstitution, the Scn2a antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Scn2a antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat brain and 2) mouse brain lysate with Scn2a antibody. Predicted molecular weight ~320 kDa.

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