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CD81 Antibody

CAT: 0800-RQ4082Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4082Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD81, also known as TAPA1, is a protein which in humans is encoded by the CD81 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, FACS: 1-3ug/10^6 cells, Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P60033
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human partial protein corresponding to amino acids F113-K201 was used as the immunogen for the CD81 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, FCM, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the CD81 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CD81 antibody is available for research use only.
Storage Conditions
After reconstitution, the CD81 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CD81 antibody should be determined by the researcher.
Location
Cytoplasmic, membranous
Image Legend
FACS testing of human PBMCs with CD81 antibody at 1ug/10^6 cells. Blue=CD81 antibody, Green=isotype control, Red=cells alone.
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