S-Adenosyl-L-methionine (tosylate)

S-Adenosyl-L-methionine (tosylate)

• CAS Number: 52248-03-0
• UNSPSC Description: S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3].
• Target Antigen: Apoptosis; Endogenous Metabolite
• Type: Natural Products
• Related Pathways: Apoptosis;Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/s-adenosyl-l-methionine-tosylate.html
• Purity: 99.01
• Solubility: H2O : 150 mg/mL (ultrasonic)
• Smiles: O[C@@H]([C@H]([C@H](N1C=NC2=C(N=CN=C21)N)O3)O)[C@H]3C[S+](CC[C@H](N)C(O)=O)C.O=S(C4=CC=C(C)C=C4)([O-])=O
• Molecular Weight: 570.64
• References & Citations: [1]G M Bressa. et al. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14.|[2]Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6.|[3]Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92(4):1515-42.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, stored under nitrogen, away from moisture)
• Clinical Information: Launched