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ADAM12 Antibody

CAT: 0800-R33112-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R33112-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Additional name (s) for this target protein: A disintegrin and metalloproteinase domain 12
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 3-5 µg/mL, IF/ICC: 10 µg/mL, FACS: 10ug/10^6 cells in 0.2ml, ELISA (peptide) LOD: 1:64000
UniProt
O43184
Host
Goat
Reactivity
Human
Immunogen
Amino acids AARPLPVSPARALC were used as the immunogen for this ADAM12 antibody. (1)
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, IF/ICC, FACS, ELISA (peptide)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Reconstitution
Aliquot and store the ADAM12 antibody at -20oC.
Limitations
This ADAM12 antibody is available for research use only.
Storage Conditions
Aliquot and store the ADAM12 antibody at -20°C.
Formulation
0.5 mg/mL in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Applications Notes
Optimal dilution of the ADAM12 antibody should be determined by the researcher.1. This Ab can detect the long and short form of the protein.
Location
Cytoplasmic, membranous
Image Legend
IHC staining of FFPE human prostate with ADAM12 antibody at 4ug/ml. HIER: steamed with pH6 citrate buffer, AP-staining.

UniProtKB · O43184

Disintegrin and metalloproteinase domain-containing protein 12

ADA12_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43184
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADAM12
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ADAM 12
EC number
3.4.24.-
Processing
Precursor
Secondary accessions
O60470, Q5JRP0, Q5JRP1, Q6P9E3, Q6UWB0
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell membraneMembraneSecreted

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinZymogen

Domain

EGF-like domainSH3-bindingSignalTransmembraneTransmembrane helix

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

Technical term

Proteomics identificationReference proteome

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