Ccl20 Antibody / Mip-3 alpha

• Description:

  Macrophage Inflammatory Protein 3 alpha (MIP-3 alpha), is also called Chemokine, cc motif, ligand 20 (CCL20) . The MIP-3 alpha / CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3 alpha is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3 alpha / CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin.

• Specifications:

  Western Blot: 0.5-1 µg/mL, ELISA (Capture; recombinant mouse protein) : 0.1-0.5 µg/mL (BSA-free format available)

• UniProt:

  O89093

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  A recombinant mouse protein corresponding to amino acids A28-M97 was used as the immunogen for the Ccl20 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB, ELISA (capture)

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

• Reconstitution:

  After reconstitution, the Ccl20 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This Ccl20 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the Ccl20 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  Optimal dilution of the Ccl20 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Cytoplasmic, secreted

• Image Legend:

  Western blot testing of 1) rat testis and 2) mouse testis tissue lysate with Ccl20 antibody at 0.5ug/ml. Predicted molecular weight ~11 kDa.