CD62L Antibody

CAT: 0800-R32855Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R32855Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a homing receptor for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, ELISA (recombinant human protein) : 0.1-0.5 µg/mL (BSA-free format available)
UniProt
P14151
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human protein corresponding to amino acids W39-K151 was used as the immunogen for the CD62L antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the CD62L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CD62L antibody is available for research use only.
Storage Conditions
After reconstitution, the CD62L antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CD62L antibody should be determined by the researcher.
Image Legend
Western blot testing of recombinant human protein with CD62L antibody at 0.5ug/ml. Expected molecular weight: 42~95 kDa depending on level of glycosylation.

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