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CXCR4 Antibody

CAT: 0800-R32743Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32743Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CXCR4 (Chemokine, CXC Motif, Receptor 4), also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. It is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is also a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1. It functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. It was concluded that PBSF/SDF-1 and CXCR4 define a new signalling system for organ vascularization.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P61073
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 265-294 (ILLEIIKQGCEFENTVHKWISITEALAFFH) from the human protein were used as the immunogen for the CXCR4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the CXCR4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CXCR4 antibody is available for research use only.
Storage Conditions
After reconstitution, the CXCR4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CXCR4 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with CXCR4 antibody at 0.5ug/ml. Predicted molecular weight ~40 kDa but may be observed at higher molecular weights due to glycosylation.

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