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CXCR6 Antibody

CAT: 0800-R31193Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31193Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chemokine CXC Motif Receptor 6, also known as STRL33 and Bonzo, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al. (1997) mapped the single-copy gene to chromosome 3. Matloubian et al. (2000) found that human and mouse cells expressing the protein showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 most likely function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al. (2001) concluded that the proteinb may be important in the trafficking of effector T cells mediating type-1 inflammation.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
O00574
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human Chemokine CXC Motif Receptor 6 (EDNSKTFSASHNVEATSMFQL) was used as the immunogen for this CXCR6 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the CXCR6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CXCR6 antibody is available for research use only.
Storage Conditions
After reconstitution, the CXCR6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the CXCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of CXCR6 antibody and Lane 1: HeLa; 2: Jurkat; 3: MCF-7 lysate. Expected/observed molecular weight: ~39 kDa.

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