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CXCR2 Antibody

CAT: 0800-R30204Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30204Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine) . Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P25025
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids CYEDMGNNTANWRMLLR were used as the immunogen for this CXCR2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CXCR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CXCR2 antibody is available for research use only.
Storage Conditions
After reconstitution, the CXCR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the CXCR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of 1) rat lung and 2) human COLO-320 cell lysate with CXCR2 antibody. Predicted molecular weight ~40 kDa.

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