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ECE1 Antibody / Endothelin converting enzyme 1

CAT: 0800-R32724Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32724Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Endothelin converting enzyme 1, also known as ECE1, is an enzyme which in humans is encoded by the ECE1 gene. The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL
UniProt
P42892
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids M18-T233 from the human protein were used as the immunogen for the ECE1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the ECE1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ECE1 antibody is available for research use only.
Storage Conditions
After reconstitution, the ECE1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ECE1 antibody should be determined by the researcher.
Image Legend
Immunohistochemical staining of FFPE human lung cancer tissue with ECE1 antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Product Datasheet
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