Angiotensin-converting enzyme 2 Antibody

• Description:

  ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator.

• Specifications:

  Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, ELISA: peptide immunogen

• UniProt:

  Q9BYF1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 773-805 from the human protein was used as the immunogen for this Angiotensin-converting enzyme 2 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, IHC, ELISA

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Angiotensin-converting enzyme 2 antibody is available for research use only.

• Storage Conditions:

  Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the Angiotensin-converting enzyme 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of the Angiotensin-converting enzyme 2 antibody in K562 lysate. Predicted molecular weight: 90-100 kDa.