Angiotensin Converting Enzyme Antibody / ACE

Angiotensin Converting Enzyme Antibody / ACE

• Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
• CAS Number: 9007-83-4
• UniProt: P12821
• Host: Mouse
• Immunogen: Full-length recombinant human protein was used as the immunogen for the Angiotensin Converting Enzyme antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Applications: ELISA, IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Aliquot the Angiotensin Converting Enzyme antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This Angiotensin Converting Enzyme antibody is available for research use only.