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TNF alpha Antibody

CAT: 0800-R32668Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32668Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TNFa (Tumor Necrosis Factor alpha) gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. And this cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Moreover, this cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P06804
Host
Rabbit
Reactivity
Mouse
Immunogen
Amino acids 202-235 (FQLEKGDQLSAEVNLPKYLDFAESGQVYFGVIAL) from the mouse protein were used as the immunogen for the TNF alpha antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the TNF alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TNF alpha antibody is available for research use only.
Storage Conditions
After reconstitution, the TNF alpha antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TNF alpha antibody should be determined by the researcher.
Image Legend
Western blot testing of mouse thymus tissue with TNF alpha antibody at 0.5ug/ml. Predicted molecular weight ~26 kDa.

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