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Catalase Antibody

CAT: 0800-R32390Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32390Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Catalase is a key antioxidant enzyme in the bodies defensing against oxidative stress. It is also a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
Gene ID
847
UniProt
P04040
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids E344-L527 of the human protein were used as the immunogen for the Catalase antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the Catalase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Catalase antibody is available for research use only.
Storage Conditions
After reconstitution, the Catalase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Catalase antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) rat skeletal muscle, 2) mouse skeletal muscle and 3) human A549 lysate with Catalase antibody. Expected/observed molecular weight ~60 kDa.

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