DMRT1 Antibody

CAT: 0800-R32367Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R32367Size:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain) . The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q9Y5R6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids RDCQCKKCNLIAERQRVMAAQVALRRQQAQE of human DMRT1 were used as the immunogen for the DMRT1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the DMRT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This DMRT1 antibody is available for research use only.
Storage Conditions
After reconstitution, the DMRT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the DMRT1 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Western blot testing of 1) rat testis and 2) mouse testis lysate with DMRT1 antibody. Expected/observed molecular weight ~39 kDa.

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