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RAB10 Antibody

CAT: 0800-R32155Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32155Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ras-related protein Rab-10 is a protein that in humans is encoded by the RAB10 gene. RAB10 belongs to the RAS superfamily of small GTPases. And RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking. The RAB10 gene is mapped to chromosome 2p23.1-p22.3 by radiation hybrid analysis. It was found that the purified recombinant GAP domain of human AS160 showed GAP activity with RAB2A, RAB8A, RAB10, and RAB14, but not with 14 other RABs. Immunoblot analysis showed that these RABs associated with Glut4-positive vesicles in mouse adipocytes. Thereby, it concluded that AK160 functions as a RAB GAP and that RABs may participate in GLUT4 translocation.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
P61026
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids AKANINIEKAFLTLAEDILRKTPVKEPNSENVD of human RAB10 were used as the immunogen for the RAB10 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the RAB10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RAB10 antibody is available for research use only.
Storage Conditions
After reconstitution, the RAB10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the RAB10 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat brain, 2) mouse thymus, 3) mouse brain, 4) human HeLa, 5) MCF7 and 6) COLO320 lysate with RAB10 antibody. Expected/observed molecular weight ~22 kDa.

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