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STAT3 Antibody

CAT: 0800-R32089Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32089Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The transcription factor, signal transducer and activator of transcription-3 (STAT-3) is the most pleiotropic member of the signal transducer and activator of transcription (STAT) family of transcription factors and mediates pivotal responses for the cytokine family. The mouse STAT3 gene contains 24 exons and spans 30 kb. The translation initiation codon is in exon 2, and the stop codon is in exon 24. STAT3 is mapped to 17q21. It contributes to various physiological processes. Hepatic STAT-3 signaling is thus essential for normal glucose homeostasis and may provide new therapeutic targets for diabetes mellitus.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Immunoprecipitation: 2ug antibody/500ug lysate, Flow cytometry: 1-3ug/million cells
UniProt
P40763
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids EKQQMLEQHLQDVRKRVQDLEQKMKVVEN of human STAT3 were used as the immunogen for the STAT3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, IP, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the STAT3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This STAT3 antibody is available for research use only.
Storage Conditions
After reconstitution, the STAT3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the STAT3 antibody should be determined by the researcher.
Location
Cytoplasmic, nuclear
Image Legend
Western blot testing of 1) human HEL, 2) human A549, 3) rat lung, 4) rat heart, 5) mouse lung and 6) mouse heart tissue lysate with STAT3 antibody. Expected molecular weight: ~92 kDa (alpha) and ~83 kDa (beta) .

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