Products for Research Use Only
RegisterLogin

SIRT7 Antibody

CAT: 0800-R31771Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31771Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sirtuin 7 a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL
UniProt
Q9NRC8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Human partial recombinant protein (AA 8-350) was used as the immunogen for this SIRT7 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
The lyophilized SIRT7 antibody can be stored at 4oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SIRT7 antibody is available for research use only.
Storage Conditions
The lyophilized SIRT7 antibody can be stored at 4°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Titration of the SIRT7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, nuclear
Image Legend
IHC-P: SIRT7 antibody staining of mouse spleen tissue.

UniProtKB · Q9NRC8

NAD-dependent protein deacetylase sirtuin-7

SIR7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NRC8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SIRT7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.1.286
Processing
—
Secondary accessions
A8K2K0, B3KSU8, Q3MIK4, Q9NSZ6, Q9NUS6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorHydrolaseRepressorTransferase

Cellular component

ChromosomeCytoplasmNucleus

Biological process

DNA damageDNA repairTranscriptionTranscription regulation

Ligand

Metal-bindingNADZinc

PTM

MethylationPhosphoproteinUbl conjugation

Related Products

CatalogName
F53070-0.4MLSirt1 Antibody
F49519-0.4MLSIRT3 Antibody
F43446-0.4MLSIRT6 Antibody
F52857-0.08MLSIRT1 Antibody
F43446-0.08MLSIRT6 Antibody
R35542-100UGSirt3 Antibody
F49521-0.08MLSIRT5 Antibody
V9647-20UGSIRT1 Antibody
F53070-0.08MLSirt1 Antibody
F43966-0.4MLSIRT5 Antibody

Alternative Products

CatalogName
70R-11612SIRT7 antibody

Popular Products