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Nod1 Antibody

CAT: 0800-R31707Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31707Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. It is a member of NOD-like receptor protein family and is a close relative of Nod2. It recognizes bacterial molecules and stimulates an immune reaction. Nod1 contains a caspase recruitment domain (CARD) . This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. Additionally, it has been shown that Nod1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, ICC (FFPE) : 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Human partial recombinant protein (AA 1-160) was used as the immunogen for this Nod1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ICC
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the Nod1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Nod1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Nod1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Nod1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Nod1 antibody and Lane 1: human A549; 2: rat heart lysate. Predicted/observed molecular weight: ~107 kDa.
Product Datasheet
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