TRPC7 Antibody

• Description:

  Transient receptor potential cation channel, subfamily C, member 7, also known as TRP7, is a human gene encoding a protein named TRPC7. It is the most abundantly expressed long TRPC in peripheral blood and in some blood cell lines. TRPC7 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. It is activated by oxidative stress and confers susceptibility to cell death.

• Specifications:

  Western blot: 0.5-1 µg/mL

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Human partial recombinant protein (AA 716-862) was used as the immunogen for this TRPC7 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

• Reconstitution:

  After reconstitution, the TRPC7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This TRPC7 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the TRPC7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  The stated application concentrations are suggested starting amounts. Titration of the TRPC7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of TRPC7 antibody and Lane 1: mouse brain; 2: human A549; 3: (h) COLO320; 4: (h) SKOV. Expected molecular weight ~100 kDa.