TRPC4 Antibody

CAT: 0800-R31431Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R31431Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The short Transient receptor potential channel 4, also known as Trp-related protein 4, is a protein that in humans is encoded by the TRPC4 gene. TRPC4 is a member of the transient receptor potential cation channels. It is mapped to 13q13.3. This protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors andtyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. TRPC4 also has an essential role in endothelial-dependent regulation of vascular tone, endothelial permeability, and neurotransmitter release from thalamic interneurons.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q9UBN4
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human Transient receptor potential channel 4 (LNLPDTVTHEDYVTTRL) was used as the immunogen for this TRPC4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the TRPC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TRPC4 antibody is available for research use only.
Storage Conditions
After reconstitution, the TRPC4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the TRPC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human 1) COLO320, 2) MCF-7 and 3) PANC lysate with TRPC4 antibody at 0.5ug/ml. Predicted molecular weight: ~112 kDa.

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