Products for Research Use Only
RegisterLogin

CYP2E1 Antibody

CAT: 0800-R31603Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31603Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cytochrome P450 2E1, a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body. In humans, the enzyme is encoded by the CYP2E1 gene. It is mapped to 10q26.3. While it is involved in the oxidative metabolism of a small range of substrates (mostly small polar molecules), there are many important drug interactions mediated by the enzyme. Most drugs undergo deactivation by CYP2E1, either directly or by facilitated excretion from the body. Also, many substances are bioactivated by CYP2E1 to form their active compounds. In addition, it is an important enzyme for the conversion of ethanol to acetaldehyde and to acetate in humans. In the conversion sequence of acetyl-CoA to glucose, CYP2E1 transforms acetone via acetol into propylene glycol and methylglyoxal, the precursors of pyruvate, acetate and lactate.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL
UniProt
P05181
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Human partial recombinant protein (AA 1-310) was used as the immunogen for this CYP2E1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the CYP2E1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CYP2E1 antibody is available for research use only.
Storage Conditions
After reconstitution, the CYP2E1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the CYP2E1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) rat liver and 2) mouse liver lysate with CYP2E1 antibody. Predicted molecular weight ~57 kDa.

Related Products

CatalogName
RQ6970Cytochrome P450 2E1 Antibody / CYP2E1
RQ5118Cytochrome P450 2E1 Antibody / CYP2E1
F54655-0.4MLCYP2S1 Antibody
F50860-0.08MLCYP2F1 Antibody
F50860-0.4MLCYP2F1 Antibody
F54655-0.08MLCYP2S1 Antibody
R31130CYP2U1 Antibody
F54519-0.2MLCYP27B1 Antibody
F50939-0.05MLCYP1A1 Antibody
R32199CYP24A1 Antibody

Alternative Products

CatalogName
20R-CR053CYP2E1 antibody

Popular Products