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HIF-1 beta Antibody

CAT: 0800-R31550Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31550Size:100 µg
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Description
HIF-1 beta is also known as ARNT or HIF1B. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. It is mapped to 1q21.3. The protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. HIF-1 beta is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. It is a structural component of the XRE-binding form of the Ah receptor. It also functions in concert with RelB in a CD30-induced negative feedback mechanism.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 416-789) was used as the immunogen for this HIF-1 beta antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the HIF-1 beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This HIF-1 beta antibody is available for research use only.
Storage Conditions
After reconstitution, the HIF-1 beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the HIF-1 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of HIF-1 beta antibody and Lane 1: HeLa; 2: 293T; 3: Jurkat; 4: U87; Lane5: COLO320. Expected/observed size ~87KD

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HIF-1 beta Antibody | 0800-R31550 | Gentaur