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IRAK1 Antibody

CAT: 0800-R31305Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31305Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin-1 receptor-associated kinase 1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinases play a critical roles in initiating innate immune response against foreign pathogens. This gene is involved in Toll-like receptor (TLR) and IL-1R signaling pathways. It encodes one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P51617
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the N-terminus of human IRAK (FLYEVPPWVMCRFYKVMDAL) was used as the immunogen for this IRAK1 antibody (100% homologous in human, mouse and rat) .
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the IRAK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IRAK1 antibody is available for research use only.
Storage Conditions
After reconstitution, the IRAK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the IRAK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of IRAK1 antibody and Lane 1: rat liver; 2: human placenta; 3: MCF-7; 4: PANC cell lysate. Predicted/observed molecular weight: ~76 kDa.

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