Products for Research Use Only
RegisterLogin

HDAC5 Antibody

CAT: 0800-R31301Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31301Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Histone deacetylase 5 is an enzyme that in humans is encodes by the HDAC5 gene. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. This gene is mapped to 17q21.31. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC5 possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is though to be associated with colon cancer.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q9UQL6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of human Histone deacetylase 5 (YKKLFSDAQPLQPLQVYQA) was used as the immunogen for this HDAC5 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the HDAC5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This HDAC5 antibody is available for research use only.
Storage Conditions
After reconstitution, the HDAC5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the HDAC5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human 1) HeLa and 2) COLO320 cell lysate with HDAC5 antibody. Predicted molecular weight ~122 kDa, observed at 122-160 kDa.

Related Products

CatalogName
F43191-0.4MLHDAC4 Antibody
R30679HDAC3 Antibody
F41123-0.08MLHDAC1 Antibody
V4274SAF-100UGHDAC7 Antibody
F41123-0.4MLHDAC1 Antibody
V9524SAF-100UGHDAC6 Antibody
F43191-0.08MLHDAC4 Antibody
V4274-100UGHDAC7 Antibody
F41165-0.08MLHDAC6 Antibody
V9744-20UGHDAC3 Antibody

Alternative Products

CatalogName
70R-37580HDAC5 antibody

Popular Products