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CTBP2 Antibody

CAT: 0800-R30631Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30631Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The E1a region of group C adenoviruses encodes 2 nearly identical proteins that are largely responsible for the oncogenic properties of adenoviruses. The CTBP1 protein binds to the C-terminal half of these E1A proteins. Its predicted that CTBP2 is a 445-amino acid protein and it is 72% identical to CTBP1. The gene is mapped to chromosome 10q26.13. CTBP2 is a mammalian corepressor that targets diverse transcriptional regulators. It bounds the short medial portion of delta-EF1 containing the PLDLSL motif and it enhances transrepression activity of delta-EF1.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Immunohistochemistry (Frozen) : 0.5-1 µg/mL, Immunocytochemistry: 0.5-1 µg/mL
UniProt
P56545
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of CTBP2 (PNQPTKHGDNREHPNEQ) was used as the immunogen for this CTBP2 antibody (100% homologous in human, mouse and rat) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IHC-F, ICC
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the CTBP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CTBP2 antibody is available for research use only.
Storage Conditions
After reconstitution, the CTBP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the CTBP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear, cell junctions
Image Legend
IHC staining of FFPE human breast cancer tissue with CTBP2 antibody. HIER: boil tissue sections in pH6 citrate buffer for 20 min and allow to cool before testing.

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