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TNF beta Antibody

CAT: 0800-R30428Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30428Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lymphotoxin (previously known as tumor necrosis factor-beta) is a lymphokine cytokine. It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al. (1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P01374
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the middle region of human TNF beta (KQNSLLWRANTDRAFL) was used as the immunogen for this TNF beta antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the TNF beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TNF beta antibody is available for research use only.
Storage Conditions
After reconstitution, the TNF beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the TNF beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of TNF beta antibody and Lane 1: recombinant human protein 10ng; 2: 5ng; 3: 2.5ng
Product Datasheet
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