Products for Research Use Only

Claudin 5 Antibody

CAT: 0800-R30145Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30145Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Claudin-5, also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80% of VCFS patients. This gene encodes a member of the claudin family. Family members are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Additionally, it plays a major role in tight junction-specific obliteration of the intercellular space.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 191-218 (RPDLSFPVKYSAPRRPTATGDYDKKNYV-human) were used as the immunogen for the Claudin-5 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Claudin 5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Claudin 5 antibody is available for research use only.
Storage Conditions
After reconstitution, the Claudin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Claudin 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Claudin-5 antibody and rat liver. Predicted molecular weight ~23 kDa.