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Claudin 2 Antibody

CAT: 0800-R30144Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30144Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Claudin 2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Human partial recombinant protein (AA 38-230) was used as the immunogen for this Claudin 2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the Claudin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Claudin 2 antibody is available for research use only.
Storage Conditions
After reconstitution, the Claudin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Claudin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Claudin 2 antibody and Lane 1: rat kidney; 2: rat liver
Product Datasheet
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