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P16INK4a Antibody

CAT: 0800-R30064Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30064Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P16 (INK4A), also known as cyclin-dependent kinase inhibitor 2A (CDKN2A), or multiple tumor suppressor 1 (MTS1) . The p16 gene (CDKN2A) was mapped to 9p21. The p16 gene encodes a negative regulator of the cell cycle. CDKN2 plays an important role during tumorigenesis or tumor progression in a significant proportion of pancreatic adenocarcinomas. Germ-line mutations in the CDKN2A tumor-suppressor gene have been linked to the development of melanoma in some families with inherited melanoma.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (Frozen) : 1-2 µg/mL--formalin or acetone fixed tissues, Immunocytochemistry: Suitable
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human p16 protein was used as the immunogen for this p16INK4a antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
DCS-50
Applications
WB, IHC-F, ICC
Purity
Ascites
Format
Ascites
Buffer
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Reconstitution
After reconstitution, the p16INK4a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This p16INK4a antibody is available for research use only.
Storage Conditions
After reconstitution, the p16INK4a antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the p16INK4a antibody may be required due to differences in protocols and secondary/substrate sensitivity.

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