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Recombinant PTEN Antibody

CAT: 0800-R20282-0.1MLSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-R20282-0.1MLSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This recombinant PTEN antibody reacts to human Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and has dual-specificity to protein phosphatase PTEN. It may also react to mouse PTEN, as predicted by immunogen homology.
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1:1000-1:2000 (1), Western blot: 1:1000-1:2000
UniProt
P60484
Host
Rabbit
Reactivity
Human
Immunogen
A peptide corresponding to the C-terminus of human PTEN was used as the immunogen for this recombinant PTEN antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
RM265
Type
Recombinant
Applications
WB, IHC
Purity
Protein A purified from animal origin-free supernatant
Format
Purified
Buffer
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide
Reconstitution
Store the recombinant PTEN antibody at -20oC (with glycerol) or aliquot and store at -20oC (without glycerol).
Limitations
This recombinant PTEN antibody is available for research use only.
Storage Conditions
Store the recombinant PTEN antibody at -20°C (with glycerol) or aliquot and store at -20°C (without glycerol) .
Formulation
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the recombinant PTEN antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse
Image Legend
IHC testing of FFPE human brain tissue with recombinant PTEN antibody at 1:1000.

UniProtKB · P60484

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

PTEN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P60484
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PTEN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.16, 3.1.3.48, 3.1.3.67
Processing
—
Secondary accessions
B2R904, F2YHV0, O00633, O02679, Q6ICT7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

ApoptosisLipid metabolismNeurogenesis

Disease

Autism spectrum disorderDisease variantTumor suppressor

Cellular component

Cell projectionCytoplasmNucleusSecretedSynapse

Molecular function

HydrolaseProtein phosphatase

Ligand

Lipid-binding

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