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PTEN Antibody

CAT: 0800-V3923SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V3923SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PTEN (phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase) contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. It was identified as a tumor suppressor that is mutated in a large number of cancers, including sporadic brain, breast, kidney, and prostate cancers.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P60484
Host
Mouse
Reactivity
Human
Immunogen
Full length human recombinant protein was used as the immunogen for this PTEN antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
PTEN/2110
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the PTEN antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PTEN antibody is available for research use only.
Storage Conditions
Store the PTEN antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the PTEN antibody should be determined by the researcher.
Location
Cytoplasmic, nuclear
Image Legend
IHC testing of human prostate carcinoma with PTEN antibody (clone PTEN/2110) . Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
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