KLF4 Antibody

• Description:

  Krueppel-like factor family members are involved in growth regulation and a wide range of developmental processes. KLF4 is highly expressed in epithelial tissues including skin and stomach/intestine. Studies have shown that KLF4 can function as both an oncogene, upregulating hSSC, and a tumor suppressor, down-regulating colorectal cancer. KLF4 is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.

• Specifications:

  Western blot: 1-3 µg/mL

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A recombinant protein fragment from N-terminal human KLF4 was used as the immunogen for this antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB

• Purity:

  Protein A Affinity Chromatography

• Format:

  Purified

• Buffer:

  1X PBS, pH 7.4

• Reconstitution:

  Aliquot the KLF4 antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.

• Limitations:

  This KLF4 antibody is available for research use only.

• Storage Conditions:

  Aliquot the KLF4 antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.

• Formulation:

  0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

• Applications Notes:

  Provided assay concentrations are suggestions only, KLF4 antibody titration may be required for optimal results.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human samples with KLF4 antibody at 1 ug/ml. Predicted molecular weight: 50-60 kDa + possible ~75 kDa (phosphorylated form) .