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KLF6 Antibody

CAT: 0800-R31644Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31644Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kruppel-like factor 6 is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Human partial recombinant protein (AA 38-205) was used as the immunogen for this KLF6 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the KLF6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This KLF6 antibody is available for research use only.
Storage Conditions
After reconstitution, the KLF6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the KLF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of KLF6 antibody and Lane 1: human placenta; 2: rat testis; 3: (h) HeLa; 4: (h) HEPG2; 5: mouse HEPA lysate. Expected size: 32~40KD

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