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TGFB1 Antibody

CAT: 0800-F55055-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F55055-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TGFB1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
P01137
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 22-50 from the human protein was used as the immunogen for this TGFB1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TGFB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TGFB1 antibody is available for research use only.
Storage Conditions
Aliquot the TGFB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TGFB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human 1) HepG2, 2) K562 and 3) Raji cell lysate using TGFB1 antibody. Predicted molecular weight: 44-50 kDa (precursor), ~25 kDa (active form) .

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