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Tgfbr1 Antibody

CAT: 0800-F44154-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F44154-0.08MLSize:0.08 mL
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Description
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q64729
Host
Rabbit
Reactivity
Mouse
Immunogen
A portion of amino acids 141-169 from the mouse protein was used as the immunogen for this Tgfbr1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Tgfbr1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Tgfbr1 antibody is available for research use only.
Storage Conditions
Aliquot the Tgfbr1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Tgfbr1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Human, Pig, Rat
Image Legend
Tgfbr1 antibody western blot analysis in mouse kidney tissue lysate. Predicted molecular weight: ~55kDa.

UniProtKB · Q64729

TGF-beta receptor type-1

TGFR1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q64729
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Tgfbr1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
TGFR-1
EC number
2.7.11.30
Processing
Precursor
Secondary accessions
A2AJN0
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisDifferentiationGrowth regulation

Ligand

ATP-bindingMagnesiumManganeseMetal-bindingNucleotide-binding

Cellular component

Cell junctionCell membraneMembraneTight junction

PTM

Disulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

KinaseReceptorSerine/threonine-protein kinaseTransferase

Technical term

Reference proteome

Domain

SignalTransmembraneTransmembrane helix
Product Datasheet
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