MAP2K2 Antibody / MEK2

CAT: 0800-F54958-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F54958-0.4MLSize:0.4 mL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:500-1:1000
UniProt
P36507
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 200-229 from the human protein was used as the immunogen for the MAP2K2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MAP2K2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MAP2K2 antibody is available for research use only.
Storage Conditions
Aliquot the MAP2K2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the MAP2K2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human 1) HeLa and 2) MOLT4 cell lysate with MAP2K2 antibody. Expected molecular weight: 45-50 kDa.
Product Datasheet
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