Products for Research Use Only

MEK2 Antibody / MAP2K2

CAT: 0800-F54450-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F54450-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25
UniProt
P36507
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 262-292 from the human protein was used as the immunogen for the MEK2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, WB, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MEK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MEK2 antibody is available for research use only.
Storage Conditions
Aliquot the MEK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the MEK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human U937 cell lysate with MEK2 antibody. Expected molecular weight: 45-50 kDa.