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GIT1 Antibody / p95-APP1

CAT: 0800-F54926-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54926-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes (from SwissProt) .
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000, Flow cytometry: 1:50-1:100 (1x10e6 cells)
UniProt
Q9Y2X7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 533-561 from the human protein was used as the immunogen for the GIT1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the GIT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This GIT1 antibody is available for research use only.
Storage Conditions
Aliquot the GIT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the GIT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human HeLa cell lysate with GIT1 antibody. Expected molecular weight: 84-95 kDa.

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