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HPGD Antibody / 15-PGDH

CAT: 0800-F54885-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54885-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HPGD is a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. This protein is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:500-1:1000
UniProt
P15428
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 184-212 from the human protein was used as the immunogen for the HPGD antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IHC-P, WB
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the HPGD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HPGD antibody is available for research use only.
Storage Conditions
Aliquot the HPGD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the HPGD antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human placental tissue lysate with HPGD antibody. Predicted molecular weight ~29 kDa.

UniProtKB · P15428

15-hydroxyprostaglandin dehydrogenase [NAD(+)]

PGDH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15428
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HPGD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
15-PGDH
EC number
1.1.1.141
Processing
—
Secondary accessions
B4DTA4, B4DU74, B4DV57, D3DP43, E7EV11, O00749, Q06F08, Q12998
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Disease

Disease variantTumor suppressor

Biological process

Fatty acid metabolismLipid metabolismProstaglandin metabolism

Ligand

NAD

Molecular function

Oxidoreductase

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