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15-PGDH Antibody / HPGD

CAT: 0800-RQ5486Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ5486Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The HPGD gene encodes a member of the short-chain non-metalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P15428
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human 15 PGDH / HPGD was used as the immunogen for the 15-PGDH antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AEFF-8
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the 15-PGDH antibody at -20oC.
Limitations
This 15-PGDH antibody is available for research use only.
Storage Conditions
Store the 15-PGDH antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the 15-PGDH antibody should be determined by the researcher.
Image Legend
Western blot testing of human SW480 cell lysate with 15-PGDH antibody. Predicted molecular weight: ~29 kDa.

UniProtKB · P15428

15-hydroxyprostaglandin dehydrogenase [NAD(+)]

PGDH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15428
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HPGD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
15-PGDH
EC number
1.1.1.141
Processing
—
Secondary accessions
B4DTA4, B4DU74, B4DV57, D3DP43, E7EV11, O00749, Q06F08, Q12998
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Disease

Disease variantTumor suppressor

Biological process

Fatty acid metabolismLipid metabolismProstaglandin metabolism

Ligand

NAD

Molecular function

Oxidoreductase

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