USP2 Antibody

• Description:

  USP2, an ubiquitin-specific protease, is selectively up regulated in bone by the osteotropic agents PTH, PTHrP and PGE2 and possibly via the PKA/cAMP pathway. It is also thought to play a role in the recycling of ubiquitin by hydrolysis of branched poly-ubiquitin from linear poly-ubiquitin chains, production of free ubiquitin from linear poly-ubiquitin chains and from certain ribosomal ubiquitin fusion proteins.

• Specifications:

  Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:1000-1:2000

• UniProt:

  O75604

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 508-538 from the human protein was used as the immunogen for the USP2 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  IHC-P, WB

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the USP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This USP2 antibody is available for research use only.

• Storage Conditions:

  Aliquot the USP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the USP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Location:

  Cytoplasmic, nuclear

• Image Legend:

  IHC testing of FFPE human kidney tissue with USP2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.