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PAN2 Antibody / USP52

CAT: 0800-RQ8005Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8005Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAB-dependent poly (A) -specific ribonuclease subunit 2, also called Inactive ubiquitin carboxyl-terminal hydrolase 52 (USP52), is an enzyme that in humans is encoded by the PAN2 gene. This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly (A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q504Q3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E. coli-derived recombinant human protein (amino acids M1-L356) was used as the immunogen for the PAN2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the PAN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PAN2 antibody is available for research use only.
Storage Conditions
After reconstitution, the PAN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PAN2 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of fixed and permeabilized human PC-3 cells with PAN2 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= PAN2 antibody.
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