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SOX2 Antibody

CAT: 0800-F54738-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54738-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
P48431
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 251-284 from the human protein was used as the immunogen for the SOX2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, WB, FACS
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SOX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SOX2 antibody is available for research use only.
Storage Conditions
Aliquot the SOX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear
Image Legend
Western blot testing of human NCCIT cell lysate with SOX2 antibody. Predicted molecular weight ~34 kDa.
Product Datasheet
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