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C1QC Antibody

CAT: 0800-F54626-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F54626-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
P02747
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 93-120 from the human protein was used as the immunogen for the C1QC antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, FACS, IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the C1QC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This C1QC antibody is available for research use only.
Storage Conditions
Aliquot the C1QC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the C1QC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IHC testing of FFPE human rectum tissue with C1QC antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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