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SFRP5 Antibody

CAT: 0800-F54368-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54368-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq].
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25
UniProt
Q5T4F7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 190-219 from the human protein were used as the immunogen for the SFRP5 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SFRP5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SFRP5 antibody is available for research use only.
Storage Conditions
Aliquot the SFRP5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the SFRP5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IHC testing of FFPE human pancreas tissue with SFRP5 antibody. HIER: steam section in pH9 EDTA for 20 min and allow to cool prior to staining.

UniProtKB · Q5T4F7

Secreted frizzled-related protein 5

SFRP5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5T4F7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SFRP5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
sFRP-5
EC number
—
Processing
Precursor
Secondary accessions
O14780, Q86TH7
Protein keywords

Molecular function

Developmental protein

Biological process

DifferentiationWnt signaling pathway

PTM

Disulfide bond

Technical term

Proteomics identificationReference proteome

Cellular component

Secreted

Domain

Signal
Product Datasheet
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